Beta inputs to motor neurons do not directly contribute to volitional force modulation

Neural oscillatory activity in the beta band (13–30 Hz) is prominent in the brain and it is transmitted partly linearly to the spinal cord and muscles. Multiple views on the functional relevance of beta activity in the motor system have been proposed. Previous simulation work suggested that pools of spinal motoneurons (MNs) receiving a common beta input could demodulate this activity, transforming it into low-frequency neural drive that could alter force production in muscles. This may suggest that common beta inputs to muscles have a direct role in force modulation. Here we report the experimental average levels and ranges of common beta activity in spinal MNs projecting to single muscles and use a computational model of a MN pool to test if the experimentally observed beta levels in MNs can influence force. When beta was modelled as a continuous activity, the amplitude needed to produce non-negligible changes in force corresponded to beta representation in the MN pool that was far above the experimental observations. On the other hand, when beta activity was modelled as short-lived events (i.e. bursts of beta activity separated by intervals without beta oscillations), this activity approximated levels that could cause small changes in force with estimated average common beta inputs to the MNs compatible with the experimental observations. Nonetheless, bursting beta is unlikely to be used for force control due to the temporal sparsity of this activity. It is therefore concluded that beta oscillations are unlikely to contribute to the voluntary modulation of force

Neutrino masses from discrete gauge symmetries

We investigate a model with an extra $Z_{2}$ gauge symmetry in the Standard Model. We assume that only the scalars and the leptons carry non-zero charge. The symmetry gives a structure to the mass matrix for the neutrinos. With two extra Higgs singlets and two extra singlet right-handed neutrinos we can build a model that fits the requirements of the MSW-solution of the Solar neutrino problem. With a third singlet right-handed neutrino it is also possible to have a 10 eV neutrino, a dark matter candidate.Comment: SNUTP 92-105, Late

Fungi isolated from Miscanthus and sugarcane: biomass conversion, fungal enzymes, and hydrolysis of plant cell wall polymers.

BackgroundBiofuel use is one of many means of addressing global change caused by anthropogenic release of fossil fuel carbon dioxide into Earth's atmosphere. To make a meaningful reduction in fossil fuel use, bioethanol must be produced from the entire plant rather than only its starch or sugars. Enzymes produced by fungi constitute a significant percentage of the cost of bioethanol production from non-starch (i.e., lignocellulosic) components of energy crops and agricultural residues. We, and others, have reasoned that fungi that naturally deconstruct plant walls may provide the best enzymes for bioconversion of energy crops.ResultsPreviously, we have reported on the isolation of 106 fungi from decaying leaves of Miscanthus and sugarcane (Appl Environ Microbiol 77:5490-504, 2011). Here, we thoroughly analyze 30 of these fungi including those most often found on decaying leaves and stems of these plants, as well as four fungi chosen because they are well-studied for their plant cell wall deconstructing enzymes, for wood decay, or for genetic regulation of plant cell wall deconstruction. We extend our analysis to assess not only their ability over an 8-week period to bioconvert Miscanthus cell walls but also their ability to secrete total protein, to secrete enzymes with the activities of xylanases, exocellulases, endocellulases, and beta-glucosidases, and to remove specific parts of Miscanthus cell walls, that is, glucan, xylan, arabinan, and lignin.ConclusionThis study of fungi that bioconvert energy crops is significant because 30 fungi were studied, because the fungi were isolated from decaying energy grasses, because enzyme activity and removal of plant cell wall components were recorded in addition to biomass conversion, and because the study period was 2 months. Each of these factors make our study the most thorough to date, and we discovered fungi that are significantly superior on all counts to the most widely used, industrial bioconversion fungus, Trichoderma reesei. Many of the best fungi that we found are in taxonomic groups that have not been exploited for industrial bioconversion and the cultures are available from the Centraalbureau voor Schimmelcultures in Utrecht, Netherlands, for all to use

Relativistic Jets from Collapsars

We have studied the relativistic beamed outflow proposed to occur in the collapsar model of gamma-ray bursts. A jet forms as a consequence of an assumed energy deposition of $\sim 10^{50}- 10^{51}$ erg/s within a $30^{\circ}$ cone around the rotation axis of the progenitor star. The generated jet flow is strongly beamed (\la few degrees) and reaches the surface of the stellar progenitor (r $\approx 3 10^{10}$cm) intact. At break-out the maximum Lorentz factor of the jet flow is about 33. Simulations have been performed with the GENESIS multi-dimensional relativistic hydrodynamic code.Comment: 6 pages, 2 figures, to appear in the proceedings of the conference "Godunov methods: theory and applications", Oxford, October 199

Basketball game-related statistics that discriminate between teams season-long success

The aim of the present study was to identify the game-related statistics that discriminate between season-long successful and unsuccessful basketball teams participating in the Spanish Basketball League (LEB1). The sample included all 145 average records per season from the 870 games played between the 2000-2001 and the 2005-2006 regular seasons. The following game-related statistics were gathered from the official box scores of the Spanish Basketball Federation: 2- and 3-point field-goal attempts (both successful and unsuccessful), free-throws (both successful and unsuccessful), defensive and offensive rebounds, assists, steals, turnovers, blocks (both made and received), and fouls (both committed and received). To control for season variability, all results were normalized to minutes played each season and then converted to z-scores. The results allowed discrimination between best and worst teams' performances through the following game-related statistics: assists (SC=0.47), steals (SC=0.34), and blocks (SC=0.30). The function obtained correctly classified 82.4% of the cases. In conclusion, season-long performance may be supported by players' and teams' passing skills and defensive preparation

Dynamical supersymmetry breaking from unoriented D-brane instantons

We study the non-perturbative dynamics of an unoriented Z_5-quiver theory of GUT kind with gauge group U(5) and chiral matter. At strong coupling the non-perturbative dynamics is described in terms of set of baryon/meson variables satisfying a quantum deformed constraint. We compute the effective superpotential of the theory and show that it admits a line of supersymmetric vacua and a phase where supersymmetry is dynamically broken via gaugino condensation.Comment: 24 pages, 1 figur

Instanton Induced Neutrino Majorana Masses in CFT Orientifolds with MSSM-like spectra

Recently it has been shown that string instanton effects may give rise to neutrino Majorana masses in certain classes of semi-realistic string compactifications. In this paper we make a systematic search for supersymmetric MSSM-like Type II Gepner orientifold constructions admitting boundary states associated with instantons giving rise to neutrino Majorana masses and other L- and/or B-violating operators. We analyze the zero mode structure of D-brane instantons on general type II orientifold compactifications, and show that only instantons with O(1) symmetry can have just the two zero modes required to contribute to the 4d superpotential. We however discuss how the addition of fluxes and/or possible non-perturbative extensions of the orientifold compactifications would allow also instantons with $Sp(2)$ and U(1) symmetries to generate such superpotentials. In the context of Gepner orientifolds with MSSM-like spectra, we find no models with O(1) instantons with just the required zero modes to generate a neutrino mass superpotential. On the other hand we find a number of models in one particular orientifold of the Gepner model $(2,4,22,22)$ with $Sp(2)$ instantons with a few extra uncharged non-chiral zero modes which could be easily lifted by the mentioned effects. A few more orientifold examples are also found under less stringent constraints on the zero modes. This class of $Sp(2)$ instantons have the interesting property that R-parity conservation is automatic and the flavour structure of the neutrino Majorana mass matrices has a simple factorized form.Comment: 68 pages, 2 figures; v2. typos corrected, refs adde

Reply to "On scaling solutions with a dissipative fluid"

In this paper we show that the claims in [Class. Quantum Grav. 19 (2002) 3067, gr-qc/0203081] related to our analysis in [Phys. Rev. D 62, 063508 (2000), astro-ph/0005070] are wrong.Comment: 4 pages, uses RevTeX. v2: To appear in Class. Quantum Gra

Supersymmetry Breaking and Determination of the Unification Gauge Coupling Constant in String Theories

We study in a systematic and modular invariant way gaugino condensation in the hidden sector as a potential source of hierarchical supersymmetry breaking and a non--trivial potential for the dilaton $S$ whose real part corresponds to the tree level gauge coupling constant (${\rm Re}\ S\sim g_{gut}^{-2}$). For the case of pure Yang--Mills condensation, we show that no realistic results (in particular no reasonable values for ${\rm Re}\ S$) can emerge, even if the hidden gauge group is not simple. However, in the presence of hidden matter (i.e. the most frequent case) there arises a very interesting class of scenarios with two or more hidden condensing groups for which the dilaton dynamically acquires a reasonable value (${\rm Re}\ S\sim 2$) and supersymmetry is broken at the correct scale ($m_{3/2}\sim 10^3\ GeV$) with no need of fine--tuning. Actually, good values for ${\rm Re}\ S$ and $m_{3/2}$ are correlated. We make an exhaustive classification of the working possibilities. Remarkably, the results are basically independent from the value of $\delta^{GS}$ (the contributions from the Green--Schwarz mechanism). The radius of the compactified space also acquires an expectation value, breaking duality spontaneously.Comment: 35 page